We worship Thine immaculate image, O Good One,/ and ask the forgiveness of our sins, O Christ our God;/ for of Thine own will Thou wast pleased to ascend the Cross in the flesh,/ to deliver from slavery to the enemy those whom Thou hadst created./ Therefore we thankfully cry to Thee:/ Thou hast filled all things with joy, O our Savior,/ by coming to save the world.
In giving birth thou didst preserve thy virginity;/ in falling asleep thou didst not forsake the world, O Theotokos./ Thou wast translated to life, O Mother of Life,/ and by your prayers you deliver our souls from death.
O Diomedes, as a healer of bodily sickness,/ by the word of truth thou didst grant healing to souls./ Thou hast received this gift from God/ and dost ever help those suffering from various diseases./ Thou art radiant with the grace of martyrdom;/ wherefore thou savest those who cry to thee:/ Glory to Him Who has glorified thee; glory to Him Who has crowned thee;/ glory to Him Who through thee works healings for all.
The uncircumscribable word of the Father/ was circumscribed when He took flesh of thee, O Mother of God;/ and when He had restored the defiled image to its pristine state He suffused it with divine beauty./ And as we proclaim our salvation we record it by word and deed.
Neither the tomb nor death could hold the Theotokos,/ who is sleepless in her intercessions and an unchanging hope in her mediations./ For as the Mother of Life she was transferred to life/ by Him Who dwelt in her ever-virgin womb.
Thou wast skilled in the science of healing/ and didst wisely choose the lot of holy athletes;/ thou didst openly preach Christ our God,/ O blessed Diomedes, thou adornment of unmercenary saints,/ the protector of those crying to thee:/ Become the physician of us thy servants, O wise one.